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超微粉碎机与其他中药粉碎设备性能对比详情

中药的超微粉碎,当前主要指细胞级微粉碎。动植物药的主要药效成份通常散布于细胞内与细胞间质,且以细胞内为主。当细胞破壁后其细胞内有效成份暴显露来,所以药效大幅度进步,而且起效速度快。目前国内开展有球磨机、行星磨、转子粉碎、气流粉碎和振动粉碎等技术与配备。
Ultra-micro comminution of traditional Chinese medicine mainly refers to cell-level micro-comminution. The main pharmacodynamic components of animal and botanical medicines are usually dispersed in cells and interstitial cells, and mainly in cells. When the cell wall is broken, the effective components of the cell are exposed, so the efficacy of the drug is greatly improved, and the onset speed is fast. At present, ball mill, planetary mill, rotor grinding, air flow grinding and vibration grinding technology and equipment are developed in China.
球磨机物料顺应性较普遍、造价低,操作维修便当,设备牢靠性好,但设备效率太低,对高韧性和纤维性物料粉体加工不能胜任。
Ball mill material compliance is common, low cost, easy operation and maintenance, equipment reliability is good, but equipment efficiency is too low, high toughness and fiber material powder processing is not competent.
行星磨固然消费效率高,但单机容量太小,且运用不便,所以采用不多。当前德国、日本对动植物药的超微粉碎均选用振动磨。但振动磨有一、二、三代之分,只要第三代振动磨是高效超微粉碎设备。它用于孢子构造的植物(粒径仅10μm)如灵芝孢子粉的破壁可在很短时间完成,其破壁率可达95%,关于任何中药均可停止超微粉碎。用于矿物药粉碎可达0.3微米。
Although planetary mill has high consumption efficiency, it is not widely used because of its small capacity and inconvenience in operation. Vibration mill is currently used in ultra-fine comminution of animal and plant medicines in Germany and Japan. However, the vibration mill can be divided into one, two and three generations, as long as the third generation of vibration mill is an efficient ultra-fine grinding equipment. It can be used in spore-forming plants (with a particle size of only 10 microns), such as Ganoderma lucidum spore powder, whose wall-breaking rate can reach 95% in a very short time. For any traditional Chinese medicine, ultrafine grinding can be stopped. It can be used for crushing mineral medicines up to 0.3 micron.
气流粉碎机国际研讨公认无法到达D50<3μm,该机只是微粉碎设备,不属超微粉碎设备,且粉碎纤维性、韧性中药十分艰难。特别在粉碎作业时存在相对高速气流,将药物的挥发份带走,形成药效损失,所以该机合适具有一定脆性的化学品微粉碎,或矿物中药的粉碎,绝不适用于动植物中药的超微粉碎。
It is generally acknowledged that the airflow pulverizer can not reach D50 < 3 micron. It is only a micro-pulverizing equipment, not a micro-pulverizing equipment, and it is very difficult to pulverize the fibrous and tough traditional Chinese medicine. Especially in the crushing operation, there is a relatively high-speed air flow, which takes the volatile components of the drugs away, resulting in the loss of efficacy. Therefore, the machine is suitable for the micro-crushing of chemicals with certain brittleness, or the crushing of mineral Chinese medicines, and it is not suitable for the ultra-crushing of animal and plant Chinese medicines.
多种带筛转子粉碎机存在料头,无法保证全组份入药,绝不能够用于中药的微粉碎,特别是复方中药的粉碎。它合适于化工行业粉碎作业。
Many kinds of rotor grinders with sieve have material heads, which can not guarantee the whole component to be used as medicine, and can never be used for the micro-grinding of traditional Chinese medicine, especially for the crushing of compound traditional Chinese medicine. It is suitable for crushing operation in chemical industry.
中药低温粉碎机
选择合理的粉碎设备对中药超微粉碎是十分重要的。
It is very important to select reasonable crushing equipment for ultrafine crushing of traditional Chinese medicine.
工艺应用
Process application
以达微机械细胞级微粉碎技术为中心的工艺应用,为中药制药技术创新提供了宽广的运作空间。
Technological application centered on micro-mechanical cell-level micro-grinding technology provides a broad operating space for the technological innovation of traditional Chinese medicine pharmaceuticals.
1、 处理了中药粉碎作业存在的各种问题
1. Dealing with various problems existing in crushing operation of traditional Chinese medicine
强纤维性(如灵芝、甘草等)       高糖高粘性(如枸杞子、麦冬等)
Strong fibre (such as Ganoderma lucidum, licorice, etc.) high sugar and high viscosity (such as wolfberry, Ophiopogon japonicus, etc.)
树 脂 类(如乳香、没药等)       强 韧 性(如羚羊角、海马等)
Resins (such as frankincense, myrrh, etc.) are tough (such as antelope horn, hippocampus, etc.)
动 物 类(如蝎子、水蛭等)       矿 物 类(如朱砂、信石等)
Animals (such as scorpions, leeches, etc.) minerals (such as cinnabar, hirudo, etc.)
2、 中药剂型变革、进步疗效、降低用药量及进步微粉工艺程度
2. Traditional Chinese Medicine Formulation Reform, Improvement of Therapeutic Effect, Reduction of Drug Consumption and Advancement of Micropowder Technology
减少用药量80%—90%,变革中药汤剂(调心调胃汤)
Reduce the dosage by 80%-90%. Change the traditional Chinese medicine decoction (Tiaoxin Tiaowei Decoction)
新型中药微粉饮片300目
300 meshes of new Chinese herbal powder pieces
生粉软胶囊制剂(人参软胶囊)
Raw Powder Soft Capsule Preparation (Ginseng Soft Capsule)
一步法膏体制备(六味地黄软胶囊)
One-step preparation of ointment (Liuwei Dihuang Soft Capsule)
完成无辅料或少辅料造粒、压片
Complete granulation and tableting without or with few excipients
高效率(zui小型设备:朱砂每小时25Kg)
High efficiency (zui small equipment: cinnabar 25Kg per hour)
以降低服用量和进步疗效为目的(八味地黄丸)
To reduce dosage and improve curative effect (Bawei Dihuang Pill)
降低药材耗费(覆盆子减少损耗20%)
Reduce the consumption of medicinal materials (raspberry reduces 20%)
高效喷雾制剂 高效透皮(膜)制剂
Highly effective spray preparation high efficiency transdermal (membrane) preparation
完成优于±1‰平均度的复合化和精细包覆 (人工牛黄)
Completion of compound and fine coating (artificial bezoar) better than (+1 average)
低温保质粉碎,新颖中草药及鲜活动物组织(乌鸡、螃蟹等)
New Chinese herbal medicines and fresh living animal tissues (black chicken, crab, etc.)
以下为局部粉碎实例:
The following are examples of local comminution:
原料       原料粒度       方式       处置时间       制品粒度       处置量    适用机型
Time of granularity disposal of raw materials and raw materials
蚕丝       长丝                      15分钟        -200目96% 5Kg/h    XDW-F100
Silk filament 15 minutes-200 mesh 96% 5Kg/h XDW-F100
灵芝       -1mm         干式     15分钟        -200目95% 15Kg/h
Ganoderma lucidum-1mm dry 15 minutes-200 mesh 95% 15Kg/h
珍珠       -2mm         干式     15分钟        -300目      50Kg/h
Pearl-2mm dry 15 minutes-300 mesh 50Kg/h
羚羊角    -2mm         干式     15分钟        -200目      15Kg/h
Antelope horn-2mm dry 15 minutes-200 mesh 15Kg/h
蝎子、蜈蚣、水蛭-2mm      干式       5分钟     -200目98%     30Kg/h
Scorpion, centipede, leech - 2mm dry 5 minutes - 200 mesh 98% 30Kg/h
葛根       -2mm         干式        14分钟   -200目 95%    30Kg/h
Pueraria lobata-2mm dry 14 minutes-200 mesh 95% 30Kg/h
干草       -1mm         干式         12分钟   -200目   30Kg/h
Hay-1mm dry 12 minutes-200 mesh 30Kg/h
八珍丸    -10目        干式         25分钟   -300目98%      30Kg/h
Bazhen pill-10 mesh dry 25 minutes-300 mesh 98% 30Kg/h
桂附地黄 -10目      干式         12分钟   -300目97%      35Kg/h
Rehmannia glutinosa-10 mesh dry 12 minutes-300 mesh 97% 35Kg/h
灵芝孢子粉    孢子   干式         25分钟   破壁率≥95%    10Kg/h
Dry 25-minute wall-breaking rate of Ganoderma lucidum sporopollen spores (>95% 10Kg/h)
铝粉       -30mm    湿式         15分钟   -10μm 90%      110Kg/h
Aluminum powder-30mm wet 15 minutes-10um 90% 110Kg/h
鲨鱼软骨 -5mm     干式         12分钟   -200目97.5%          1.6Kg/h    XDW-6
Shark cartilage-5mm dry 12 minutes-200 mesh 97.5% 1.6Kg/h XDW-6
朱砂       -5mm       干式         5分钟     3μm           24Kg/h
Cinnamon-5mm dry 5 minutes 3 micron 24 Kg/h
鹿角       -1mm       干式         15分钟   -150目          1.35Kg/h
Antler-1mm dry 15 minutes-150 mesh 1.35Kg/h
尼莫地平 -2mm       干式         2.5分钟 -3μm 90%       17Kg/h
Nimodipine-2mm dry 2.5min-3um 90% 17Kg/h
大蒜       -1mm         湿式(豆油)      5分钟     -400目95%      9.6Kg/h
Garlic-1mm wet (soybean oil) 5 minutes-400 mesh 95% 9.6Kg/h
天门冬    -10目        干式(低温) 15分钟   -200目95%      1Kg/h
Asparagus - 10 mesh dry type (low temperature) 15 minutes - 200 mesh 95% 1Kg/h
乳香       -2mm         干式         12分钟   -200目95%      1.25 Kg/h
Frankincense-2mm dry 12 minutes-200 mesh 95% 1.25 Kg/h
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